How Science Supports the Benefits
Whole-plant extract contains cannabinoids, which are chemical compounds within the hemp plant that have been reported, both from anecdotal evidence and pre-clinical studies*, to offer relief from a multitude of ailments.
Structurally, cannabinoids resemble endocannabinoids which are compounds our bodies naturally produce to balance and control communication between cells as well as promote cellular health.
Research indicates that many unpleasant symptoms and diseases occur when a deficiency or other problem impacts the endocannabinoid system (eCS). The primary function of the eCS is to maintain homeostasis. It allows cells to communicate with other cells and their external environment and facilitates cells doing whatever is necessary to be healthy. Cannabinoids have been shown to bind to a number of different receptor sites in the brain and body, and have different effects based on which receptors they bind to and how they interact.
The most well-known receptor interactions are those between cannabinoids and CB1 and CB2 receptors which are the primary receptors in the eCS. CB1 receptors are concentrated in the brain and central nervous system while CB2 receptors are concentrated in the peripheral immune system.
CB1 receptors regulate:
- Learning and memory
- Neuronal development and synaptic plasticity
- Reward and addiction
- Neuroinflammation and degeneration
- Metabolism and food intake
- Bone mass
- Cardiovascular effects
CB2 receptors regulate:
- Allergic and autoimmune inflammatory disease
- Neurodegenerative disease
- Ischemic injury from stroke or heart attack
- Chronic pain
- Hepatic injury and disease
- Alcohol and nicotine addiction
- Weight gain
- Stress response
Receptors function at a base level of activity. When cannabinoids, like those found in activated hemp extract, bind to these receptors, the receptors either do more or less of what they were doing. For example, inflammation is a common cause of discomfort. When cannabinoids interact with CB2 receptors, some studies indicate that it reduces the inflammatory response. It has also been reported that activated hemp extract interacts with CB2 receptors on cancer cells by recognizing these cells are not healthy and initiating apoptosis (a sequence of biochemical reactions that results in cell death).
With an increasing understanding of the effects of cannabinoids, patients can now tailor their cannabinoid therapy regime to the type of relief they need.
Learn More About Hemp
Whole-plant hemp extract is a combination of the most prevalent therapeutic, activated compounds in the hemp plant. It offers numerous benefits without altering your mental state. For decades, medical professionals and the general public overlooked hemp extract because other plant remedies took center stage.
Now, the medicinal potential of hemp extract has made its way to mainstream audiences. Preclinical trials over the past four decades have found that cannabinoids, like those found in hemp extract, show potential to be a natural anti-inflammatory, antioxidant, neuroprotectant, antidepressant, and many other benefits.